Artículos
The literature on musculoskeletal tumors continues to be robust; however, it has been dominated by retrospective observational studies. For bone sarcomas, cytotoxic chemotherapy remains the mainstay of systemic therapy, with no new, effective,
targeted biologic interventions.
There has been a renewed focus on functional outcomes and socioeconomic factors associated with oncologic outcomes and ongoing interest in pelvic reconstruction, which continues to have high rates of surgical complications.
Limb reconstruction with biologic constructs, endoprosthetics, or a combination thereof continues to be successful in limb salvage, with higher revision rates in the pediatric population.
With regard to skeletal metastases, there is growing interest in advanced radiation therapy protocols, machine learning algorithms for predicting patient survival, and expansion of the indications for resection and reconstruction rather than internal fixation for long-bone metastases, due to longer life expectancies in many patients with advanced carcinomas.
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